Medical Devices

Design History Files Through Post-Market Surveillance

Complete design control documentation from concept through commercial distribution. Maintain traceability across every phase of the medical device lifecycle.

The Challenges

What Medical Device Teams Deal With Every Day

1

Design History File Management

FDA requires a complete Design History File for every medical device. Managing DHFs across documents, spreadsheets, and email chains creates compliance gaps.

2

Design Control Traceability

Tracing design inputs to outputs, verification to validation, and requirements to test results must be seamless. Disconnected systems break the traceability matrix.

3

Post-Market Surveillance Documentation

Complaint handling, CAPA management, and post-market clinical follow-up all generate documentation that must be linked back to design records.

4

Multi-Standard Compliance

FDA QSR, ISO 13485, EU MDR, and IEC 62304 each have overlapping but distinct documentation requirements. Manual compliance management is unsustainable.

How ELN Suite Helps

Built for Medical Device Workflows

Design History File Management

Complete DHF management in one platform — design inputs, outputs, reviews, verification, validation, and design transfer. Every document linked, versioned, and audit-ready.

  • Structured DHF templates per FDA guidance
  • Design input/output linking and traceability
  • Design review documentation with electronic signatures
  • Design transfer records and production readiness
Design History File — Device DHF-2026-03 Phase: V&V
Inputs
Outputs
Review
V&V
Transfer
Design Inputs (REQ)
24 requirements
Approved
Design Outputs (SPEC)
18 specifications
Approved
Design Review (DR-3)
All items closed
Complete
Verification Protocols
12 tests
8/12 Complete
Validation Protocols
6 studies
Not Started
Risk Analysis (ISO 14971)
FMEAs current
Approved

Design Control Traceability

Build and maintain your traceability matrix within the ELN Suite. Link requirements to design outputs, verification protocols to test results, and risks to mitigations.

  • Requirements traceability matrix management
  • Verification and validation protocol templates
  • Test result linking to design specifications
  • Risk management integration (ISO 14971)
Requirements Traceability Matrix 94% Linked
Requirement
Design Output
Verification
Validation
REQ-001
SPEC-001 ✓
VP-001 ✓
VAL-001 ✓
REQ-002
SPEC-002 ✓
VP-002 ✓
VAL-002 ○
REQ-003
SPEC-003 ✓
VP-003 ○
REQ-004
SPEC-004 ✓
VP-004 ✓
VAL-003 ✓

FDA QSR & ISO 13485 Compliance

Built-in workflows for both FDA Quality System Regulation and ISO 13485 requirements. Automated audit trails, CAPA management, and controlled document workflows.

  • FDA 21 CFR Part 820 compliance workflows
  • ISO 13485 quality management documentation
  • CAPA tracking with root cause analysis
  • Management review and quality objective tracking
Audit Package Generator Ready
Complete Audit Trail Report
247 pages
PDF
Electronic Signature Log
89 signatures
PDF
SOP Revision History
34 documents
PDF
Training Records
All current
PDF
Raw Data Export
Full dataset
ZIP

Post-Market Surveillance

Document complaint investigations, adverse event reports, and post-market clinical follow-up. Link surveillance findings back to design records for continuous improvement.

  • Complaint handling and investigation tracking
  • Adverse event and MDR reporting documentation
  • Post-market clinical follow-up records
  • Trend analysis and signal detection
Quality Control Dashboard All Passing
48
Tests Today
97.9%
Pass Rate
1
OOS Events
Levey-Jennings — Glucose Control
-2SDMean+2SD

Controlled Document Management

SOPs, work instructions, and specifications managed with formal review and approval workflows. Version control, change management, and distribution tracking built in.

  • Formal document review and approval workflows
  • Version control with complete change history
  • Change management with impact assessment
  • Training records linked to document revisions
FDA 21 CFR Part 11 — Audit Trail Compliant
Electronic signature applied10:47 AM
Dr. S. Chen
Meaning: "I approve this data as reviewed"
Record locked — SHA-256 hash generated10:32 AM
System
Hash: 7f83b1657ff1fc53b92dc...a4b9
Peer review approved10:15 AM
Dr. M. Torres
All ALCOA+ checks passed
Results table modified09:48 AM
Dr. S. Chen
Added row 4 — previous version preserved (v3→v4)
Experiment created from SOP-012209:02 AM
Dr. S. Chen
Template: Protein Binding Assay Protocol v3.2
Compliance

Regulations We Cover

Not generic “we support compliance” — specific, deep regulatory coverage.

FDA 21 CFR Part 820

Quality System Regulation for medical device design, manufacturing, and distribution

ISO 13485

Quality management systems for medical devices — regulatory requirements

EU MDR 2017/745

European Medical Device Regulation for CE marking and market access

ISO 14971

Application of risk management to medical devices

IEC 62304

Medical device software lifecycle process requirements

FDA 21 CFR Part 11

Electronic records and signatures for regulated medical device documentation

See How ELN Suite Fits Your Medical Device Team

Schedule a demo tailored to medical device workflows — design controls, DHF management, and post-market surveillance.

Personalized demo · No credit card required · Response within 1 business day